ASTAXANTHIN 2% (HAEMATOCOCCUS PLUVIALIS)(ALGAE)

Astaxanthin, a potent keto-carotenoid, is renowned for its vibrant red-orange pigmentation and exceptional biological activities. This ingredient, Astaxanthin 2% from Haematococcus pluvialis, is derived from a unique freshwater microalga that accumulates high concentrations of astaxanthin under stress conditions, such as nutrient deprivation or intense light exposure. Unlike other carotenoids like beta-carotene, astaxanthin lacks a beta-ionone ring, meaning it cannot be converted to Vitamin A in the body, thereby avoiding any potential pro-vitamin A toxicity. Its distinct molecular structure, featuring polar end groups and a non-polar central chain, allows it to embed within and span across cell membranes, providing comprehensive protection against oxidative stress both inside and outside the cell. This unique membrane-spanning capability is a key factor in its superior antioxidant efficacy compared to many other well-known antioxidants.

The health benefits attributed to astaxanthin are extensive, primarily stemming from its powerful antioxidant and anti-inflammatory properties. Scientific research indicates that astaxanthin is significantly more potent than other antioxidants, with studies suggesting it can be up to 6,000 times stronger than Vitamin C and 550 times stronger than Vitamin E in singlet oxygen quenching. Its anti-inflammatory effects are mediated through the modulation of various signaling pathways, including NF-κB, which helps to reduce the production of pro-inflammatory cytokines. Clinical studies have demonstrated its efficacy in supporting eye health, notably by reducing eye fatigue and improving visual acuity, possibly by crossing the blood-retinal barrier to protect photoreceptor cells. Furthermore, astaxanthin contributes to skin health by mitigating UV-induced oxidative damage, enhancing skin elasticity, and improving moisture content, as evidenced in human clinical trials.

Astaxanthin 2% from Haematococcus pluvialis is a versatile ingredient for a range of supplement formulations, including softgels, capsules, and functional foods. When incorporating astaxanthin, it is crucial to consider its stability, as carotenoids can be susceptible to oxidation; proper formulation and packaging are essential to preserve its efficacy. Research highlights the superior bioavailability and antioxidant activity of natural astaxanthin derived from H. pluvialis compared to synthetic forms, primarily due to its distinct esterified structure. For instance, a meta-analysis published in the Journal of Clinical Biochemistry and Nutrition reviewed multiple human trials, confirming astaxanthin's role in improving markers of oxidative stress and inflammation. Typical dosages in supplements range from 4mg to 12mg daily, depending on the targeted health benefit, providing a robust, science-backed solution for various health applications.