BERGAMOT EXTRACT 20:1 (CITRUS BERGAMIA)

Bergamot Extract 20:1 (Citrus bergamia) is a highly concentrated botanical ingredient derived from the fruit of the bergamot orange, a distinctive citrus species predominantly cultivated in the sun-drenched coastal regions of Calabria, Southern Italy. This unique fruit is renowned not only for its aromatic essential oil, widely used in perfumery and aromatherapy, but also for its rich phytochemical profile, particularly its high concentration of beneficial flavonoids. Our 20:1 extract signifies a potent concentration, meaning that 20 parts of the raw bergamot fruit were used to produce 1 part of the finished extract, ensuring a robust delivery of its active compounds. Historically, bergamot has been utilized in traditional Mediterranean practices for its perceived health-promoting properties, laying the groundwork for modern scientific investigation into its therapeutic potential as a dietary supplement ingredient. Its distinct tart flavor and vibrant aroma are secondary to its profound biochemical composition, which makes it a valuable addition to various health formulations.

The primary health benefits of Bergamot Extract are attributed to its unique spectrum of polyphenolic flavonoids, particularly brutieridin, melitidin, naringin, and neohesperidin. These compounds exert their effects through multiple mechanisms of action, most notably by influencing lipid metabolism. Research indicates that bergamot flavonoids can help modulate cholesterol synthesis in the liver by inhibiting HMG-CoA reductase, an enzyme critical in the endogenous production of cholesterol, akin to the action of pharmaceutical statins but through a natural pathway. Furthermore, these bioactive compounds are believed to enhance LDL receptor activity, facilitating the clearance of low-density lipoprotein (LDL) cholesterol from the bloodstream. Beyond lipid regulation, bergamot flavonoids also possess potent antioxidant properties, neutralizing free radicals and reducing oxidative stress, which is a key contributor to cardiovascular disease progression. Scientific studies, including those published in the Journal of Clinical Lipidology, have consistently demonstrated its capacity to support healthy cholesterol levels, improve triglyceride profiles, and enhance high-density lipoprotein (HDL) cholesterol, thereby contributing to overall cardiovascular wellness.

Given its scientifically validated benefits, Bergamot Extract 20:1 is an ideal ingredient for formulations targeting cardiovascular health, metabolic syndrome support, and broad-spectrum antioxidant protection. It is commonly incorporated into dietary supplements in various forms, including capsules, tablets, and powdered blends, often alongside other synergistic ingredients like CoQ10, omega-3 fatty acids, or plant sterols to amplify its effects. When selecting a bergamot extract, quality and standardization are paramount. A reputable extract should be standardized to a specific percentage of its key flavonoids, such as bergamottin or brutieridin/melitidin, to ensure consistent potency and efficacy across batches. Rigorous third-party testing for purity, heavy metals, pesticides, and microbial contaminants is essential to guarantee a safe and high-quality product. Clinical trials, such as those detailed in Phytomedicine, have further substantiated the efficacy and safety profile of bergamot extract in human subjects, demonstrating significant improvements in lipid parameters without major adverse effects, solidifying its role as a valuable, evidence-based ingredient in the supplement industry.