FISETIN 98% (RHUS SUCCEDANEA)(STEM)

Fisetin 98% is a premium-grade flavonoid derived from the stem of Rhus succedanea, also known as the Japanese wax tree or lacquer tree. This natural polyphenol, renowned for its vibrant yellow pigment, is meticulously extracted and purified to achieve an exceptional 98% concentration, ensuring maximum potency and efficacy for supplement formulations. While present in various fruits and vegetables like strawberries, apples, and onions, the concentration in Rhus succedanea stems provides a sustainable and potent source for commercial applications. Its chemical structure, a flavonol, positions it within a class of compounds widely studied for their diverse biological activities. The stringent purification process guarantees a high-quality ingredient, free from contaminants, making it a reliable choice for advanced nutritional products aimed at supporting cellular health and longevity. This highly concentrated form allows for precise dosing and optimal bioavailability in various supplement matrices.

The therapeutic potential of Fisetin stems primarily from its robust senolytic and antioxidant properties, making it a subject of extensive scientific inquiry. Research indicates Fisetin selectively induces apoptosis in senescent cells, often referred to as "zombie cells," which accumulate with age and contribute to inflammation and tissue dysfunction. This senolytic action has been demonstrated in preclinical studies, suggesting a significant role in promoting healthy aging and mitigating age-related decline. Furthermore, Fisetin acts as a potent antioxidant, neutralizing free radicals and reducing oxidative stress, a key driver of cellular damage and various chronic conditions. Studies published in journals like Nature Medicine have highlighted its ability to enhance cellular resilience and support mitochondrial function. Beyond its senolytic effects, Fisetin exhibits neuroprotective capabilities, crossing the blood-brain barrier to support cognitive function and neuronal health, as evidenced by its ability to modulate signaling pathways crucial for memory and learning.

Fisetin 98% is highly valued in the nutraceutical industry for its versatility in various supplement formulations, including capsules, powders, and functional foods targeting anti-aging, cognitive health, and overall wellness. Its high purity ensures consistent formulation and predictable biological activity. Quality control measures, including advanced analytical techniques, confirm the 98% purity and absence of impurities, adhering to stringent industry standards. Clinical research continues to explore Fisetin's broad spectrum of benefits. For instance, a randomized, double-blind, placebo-controlled pilot study published in EBioMedicine investigated Fisetin's impact on markers of senescence in older adults, showing promising results in reducing senescent cell burden. Its synergistic potential with other longevity compounds, such as quercetin or resveratrol, is also being explored to amplify its benefits. As scientific understanding expands, Fisetin 98% is poised to become a cornerstone ingredient in advanced health and wellness supplements, offering a powerful, evidence-backed solution for healthy aging.