Granular Diindolymethane (DIM)(20-60 Mesh)

Granular Diindolymethane (DIM) is a naturally occurring compound derived from the digestion of indole-3-carbinol (I3C), a phytonutrient found abundantly in cruciferous vegetables such as broccoli, cabbage, cauliflower, and Brussels sprouts. When these vegetables are consumed, I3C is converted into DIM in the stomach's acidic environment. This particular granular form, specified as 20-60 Mesh, indicates a precise particle size distribution engineered for optimal handling characteristics. This granulation enhances flowability, reduces dustiness, and improves the dispersibility and dissolution rates of the raw material, making it ideal for various supplement formulations. Its stability and ease of integration into manufacturing processes are significant advantages over finer, less manageable powders, ensuring consistent product quality and dosing accuracy.

DIM is widely recognized for its profound influence on estrogen metabolism, a critical process for both men and women. Scientific research indicates that DIM promotes a healthier balance of estrogen metabolites by encouraging the production of 2-hydroxyestrone (2-OHE1), often referred to as the "good" estrogen, while reducing the levels of 16-alpha-hydroxyestrone (16α-OHE1), which is associated with less favorable biological activities. This shift in metabolism is crucial for maintaining hormonal equilibrium and supporting cellular health. Beyond its direct impact on estrogen, DIM also exhibits antioxidant and anti-inflammatory properties, contributing to overall cellular protection against oxidative stress and inflammatory responses, as evidenced by various in vitro and preclinical studies on its molecular mechanisms.

In supplement formulations, granular DIM (20-60 Mesh) is a preferred choice for products targeting hormonal balance, women's health, men's prostate health, and detoxification support. Its improved physical properties facilitate its incorporation into capsules, tablets, and powdered blends, ensuring uniform distribution and dosage. Clinical studies have investigated DIM's potential role in supporting prostate health, breast health, and managing symptoms associated with hormonal fluctuations. For instance, research published in journals like *Nutrition and Cancer* has explored DIM's modulatory effects on estrogen receptor pathways. To maximize its bioavailability, DIM is often co-formulated with absorption enhancers such as piperine, as DIM itself can have limited systemic absorption. Sourcing high-purity, standardized granular DIM is paramount to ensure efficacy and safety in finished products, reflecting a commitment to evidence-based supplementation.