Irvingia gabonensis IGOB 131®

Irvingia gabonensis, commonly known as African Mango, is a fruit-bearing tree native to the tropical rainforests of West and Central Africa. The seed kernels of this fruit have been traditionally used in regional cuisine and folk medicine for centuries. IGOB 131® represents a proprietary, standardized extract derived from these kernels, specifically engineered to concentrate the bioactive compounds responsible for its acclaimed health benefits. This particular extract is distinguished by its precise manufacturing process, ensuring a consistent phytochemical profile and potency. Unlike generic African Mango extracts, IGOB 131® has been the subject of dedicated research, providing a scientific basis for its efficacy. Its rich composition includes a unique blend of soluble fiber, proteins, and specific phytochemicals, making it a multifaceted ingredient for modern supplement formulations targeting metabolic health and weight management.

The primary mechanisms of action for IGOB 131® are multifaceted, focusing on metabolic regulation. Research suggests that its soluble fiber content can help delay gastric emptying, contributing to increased satiety and reduced caloric intake. Furthermore, studies indicate that IGOB 131® may modulate adipogenesis by influencing the expression of genes involved in fat and glucose metabolism, such as leptin and adiponectin. Leptin, a hormone that regulates appetite and energy balance, and adiponectin, which plays a role in fatty acid breakdown and glucose regulation, are key targets. Clinical investigations have shown IGOB 131® to support healthy levels of these hormones, potentially leading to improved fat utilization and glucose homeostasis. Additionally, the extract has been implicated in inhibiting glycerol-3-phosphate dehydrogenase, an enzyme involved in converting glucose into triglycerides, thereby potentially reducing fat accumulation.

Formulators can integrate IGOB 131® powder into various dietary supplement applications, including capsules, tablets, and functional food matrices designed for weight management and metabolic support. The ingredient's robust scientific backing, particularly the specific IGOB 131® extract, provides a strong foundation for product claims. For instance, a double-blind, placebo-controlled study published in Lipids in Health and Disease demonstrated significant reductions in body weight, body fat, and improvements in metabolic parameters, including blood glucose, C-reactive protein, and cholesterol levels, in subjects receiving IGOB 131® compared to placebo. This evidence underscores its potential as a premium ingredient. Quality considerations for IGOB 131® include ensuring the extract's standardization to its active constituents and adherence to stringent purity and safety standards, making it a reliable choice for high-quality health formulations.