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VITAMIN K2 MK-4 1.3% OIL EXCIPIENT:SUNFLOWER SEED OIL
Vitamin K2 MK-4, delivered as a highly bioavailable 1.3% oil in sunflower seed oil, is a crucial fat-soluble nutrient essential for optimal bone and cardiovascular health. It supports proper calcium utilization, activating key proteins for bone mineralization and inhibiting arterial calcification, making it an ideal ingredient for advanced supplement formulations.
Description
Vitamin K2, specifically menaquinone-4 (MK-4), is a vital fat-soluble vitamin recognized for its indispensable role in numerous physiological processes beyond mere blood coagulation. This particular ingredient, VITAMIN K2 MK-4 1.3% OIL, presents MK-4 in a highly bioavailable form, meticulously standardized to 1.3% concentration and expertly dispersed in a sunflower seed oil excipient. MK-4 is naturally found in animal-derived foods like certain dairy products, egg yolks, and organ meats, making dietary intake variable. The sunflower seed oil serves not only as a neutral, stable carrier but also significantly enhances the absorption of this lipid-soluble vitamin, ensuring optimal delivery to the body's tissues. Its formulation as an oil provides a versatile solution for supplement manufacturers, facilitating its integration into various product formats while maintaining its integrity and efficacy from production to consumption.
The profound health benefits of Vitamin K2 MK-4 primarily revolve around its critical functions in bone and cardiovascular health, mediated through the activation of specific K-dependent proteins. For skeletal integrity, MK-4 acts as a crucial cofactor for the carboxylation of osteocalcin, a protein produced by osteoblasts that is essential for binding calcium to the bone matrix. Without adequate MK-4, osteocalcin remains inactive, impairing calcium integration and potentially compromising bone mineral density. Research, including studies published in the Journal of Bone and Mineral Research, consistently demonstrates MK-4's efficacy in supporting bone strength and reducing fracture risk. Concurrently, MK-4 plays a pivotal role in cardiovascular wellness by activating Matrix Gla Protein (MGP), which is a potent inhibitor of arterial calcification. Inactive MGP contributes to calcium deposition in arterial walls, leading to arterial stiffness and compromised vascular function. Clinical trials have indicated that sufficient K2 intake can help maintain arterial elasticity and support overall heart health.
This Vitamin K2 MK-4 1.3% Oil is highly adaptable for diverse supplement formulations, including softgels, liquid drops, and functional food applications where an oil-based ingredient is suitable. The manufacturing process adheres to stringent quality controls, ensuring the purity, potency, and stability of the MK-4 content. The sunflower seed oil excipient is chosen for its stability, neutral flavor profile, and wide acceptance in the nutraceutical industry, providing a robust matrix for the delicate vitamin. Scientific evidence underpinning MK-4's benefits is extensive; for instance, a comprehensive meta-analysis in Osteoporosis International highlighted MK-4's significant role in reducing fracture incidence, particularly in postmenopausal women. Furthermore, large-scale epidemiological studies, such as the landmark Rotterdam Study, have established a compelling inverse correlation between higher dietary K2 intake and reduced risk of severe aortic calcification and cardiovascular mortality. Its rapid absorption and systemic distribution underscore MK-4 as a superior form of K2 for targeted therapeutic and prophylactic applications, offering a reliable solution for enhancing bone and vascular health.
Key Benefits
- Supports bone mineral density and strength by activating osteocalcin.
- Promotes arterial flexibility and cardiovascular health by activating Matrix Gla Protein (MGP).
- Facilitates proper calcium utilization and distribution throughout the body.
- Aids in the activation of essential K-dependent proteins for various physiological processes.
Primary Uses
- Bone health supplements, often synergistic with Vitamin D3 and Calcium.
- Cardiovascular support and arterial health formulations.
- Anti-aging and longevity dietary supplements.
- Liquid dietary supplements, softgels, and functional food applications.
Active Compounds
- Menaquinone-4 (MK-4)
- Vitamin K2
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