VITAMIN K (AS VITAMIN K2)(MENAQUINANE-7) K2VITAL™

Vitamin K2, specifically as Menaquinone-7 (MK-7), is a fat-soluble vitamin crucial for several physiological processes, distinct from Vitamin K1 (phylloquinone) found predominantly in leafy green vegetables. K2VITAL™ represents a highly bioavailable and stable form of MK-7, derived through a proprietary synthesis process ensuring exceptional purity and consistency. Unlike K1, which primarily supports hepatic coagulation, K2 (MK-7) plays a pivotal role in extrahepatic tissues, particularly in calcium homeostasis. Its unique long-chain structure, with seven isoprenoid units, contributes to its extended half-life in the bloodstream, allowing for more efficient and sustained delivery to target tissues. This superior bioavailability is a key characteristic that differentiates MK-7 from shorter-chain menaquinones and Vitamin K1, making it a preferred choice for dietary supplementation aimed at systemic health benefits. The K2VITAL™ ingredient is meticulously manufactured to meet stringent quality standards, ensuring a reliable and potent source of this essential nutrient.

The primary mechanism of action for Vitamin K2 (MK-7) involves its role as a cofactor for gamma-glutamyl carboxylase (GGCX), an enzyme responsible for activating specific proteins through carboxylation. These Vitamin K-dependent proteins (VKDPs) include osteocalcin in bone and Matrix Gla Protein (MGP) in vascular tissue. Activated osteocalcin is essential for binding calcium to the bone matrix, thereby facilitating bone mineralization and strength. Conversely, activated MGP actively inhibits vascular calcification by binding to and removing calcium crystals from arterial walls, preventing their deposition. Research, such as studies published in the Journal of Nutrition and Metabolism, has demonstrated that MK-7 supplementation significantly increases the activation of these VKDPs, leading to improved bone mineral density and reduced arterial stiffness. This dual action underscores MK-7's critical involvement in directing calcium to where it is needed (bones) and away from where it is harmful (arteries), providing comprehensive support for skeletal and cardiovascular health.

K2VITAL™ MK-7 is a versatile ingredient widely applied in dietary supplements targeting bone health, cardiovascular support, and healthy aging formulations. Its stability makes it suitable for various dosage forms, including capsules, tablets, and functional foods. When formulating, K2VITAL™ is often combined with Vitamin D3, as these two vitamins work synergistically: Vitamin D3 enhances calcium absorption, while Vitamin K2 ensures proper calcium utilization within the body. Clinical trials, including a notable Rotterdam Study, have linked higher dietary intake of K2 (specifically MK-7) with a reduced risk of coronary heart disease and all-cause mortality, reinforcing its cardiovascular benefits. Furthermore, studies like the one in Osteoporosis International have shown MK-7 supplementation can improve bone strength and reduce the risk of fractures in postmenopausal women. Manufacturers prioritize K2VITAL™ for its documented efficacy, superior bioavailability, and consistent quality, underpinned by robust scientific evidence and a commitment to regulatory compliance, ensuring a premium ingredient for high-performance products.