LEMON BALM EXTRACT 10:1 (MELISSA OFFICINALIS)(STEM, LEAVES, FLOWER)

Lemon Balm Extract 10:1, derived from Melissa officinalis (stem, leaves, and flower), is a highly concentrated botanical ingredient renowned for its anxiolytic and sedative properties. A member of the mint family (Lamiaceae), Lemon Balm is native to Europe, North Africa, and West Asia, and has been traditionally utilized for centuries to calm the nerves, alleviate stress, and promote restful sleep. The 10:1 concentration signifies that ten parts of the raw plant material are used to produce one part of this potent extract, ensuring a higher density of its beneficial compounds. Its characteristic gentle lemony aroma, a hallmark of its volatile oil content, is indicative of the rich phytochemical profile responsible for its therapeutic effects. This extract offers a standardized approach to harnessing the herb's historical efficacy in modern supplement formulations, appealing to consumers seeking natural solutions for mental well-being.

The primary health benefits of Lemon Balm Extract stem from its complex array of bioactive compounds, notably rosmarinic acid, a potent phenolic compound, along with terpenes like citral, citronellal, and geraniol, and various flavonoids. Scientific research indicates that rosmarinic acid plays a crucial role by inhibiting GABA transaminase, an enzyme responsible for breaking down gamma-aminobutyric acid (GABA), a neurotransmitter that promotes relaxation and reduces neuronal excitability. This mechanism is believed to increase GABA availability in the brain, contributing to its calming effects. Furthermore, studies suggest that Lemon Balm's terpenes may interact with muscarinic and nicotinic acetylcholine receptors, influencing mood and cognitive function. A randomized, placebo-controlled trial published in *Phytotherapy Research* demonstrated that Lemon Balm significantly improved mood and reduced stress in participants, supporting its traditional use for emotional balance.

In supplement formulations, Lemon Balm Extract 10:1 is commonly applied in capsules, tablets, tinctures, and functional beverages targeting stress relief, sleep support, and cognitive enhancement. The selection of a high-quality, concentrated extract like 10:1 ensures consistent potency and efficacy, which is critical for product reliability. Manufacturers often standardize the extract for rosmarinic acid content to guarantee a consistent level of active compounds. Research published in the *Journal of Ethnopharmacology* has reviewed the clinical evidence for Lemon Balm, concluding that it is effective for mild-to-moderate anxiety and sleep disturbances. Furthermore, its antioxidant properties, attributed to its phenolic compounds, provide an additional layer of health benefit, supporting cellular protection. Combining Lemon Balm with other adaptogens or sleep-supportive ingredients like valerian root or chamomile can further enhance synergistic effects, making it a versatile ingredient for comprehensive wellness products.