LUTEOLIN (SOPHORA JAPONICA)(BUD)

Luteolin is a potent flavonoid, a type of plant-derived polyphenol, widely distributed in various botanical sources including fruits, vegetables, and medicinal herbs. Our Luteolin is meticulously extracted from the buds of Sophora japonica, commonly known as the Japanese Pagoda Tree. This particular source is renowned for its high concentration and purity of luteolin, making it a preferred raw material in the supplement industry due to its consistent phytochemical profile. As a yellow crystalline compound, luteolin plays a crucial role in plant physiology, often acting as a natural pigment and providing protective mechanisms against environmental stressors. Its chemical structure, characterized by hydroxyl groups at positions 3', 4', 5, and 7, is key to its extensive biological activity. The careful extraction from Sophora japonica buds ensures a standardized and high-quality ingredient, ready for diverse nutraceutical applications where purity and potency are paramount.

The health benefits attributed to luteolin are largely due to its multifaceted mechanisms of action, primarily centered around its powerful antioxidant and anti-inflammatory properties. Research indicates that luteolin can effectively scavenge free radicals and reactive oxygen species, thereby mitigating oxidative stress, a significant contributor to cellular damage and various chronic conditions. Furthermore, luteolin has been shown to modulate inflammatory pathways by inhibiting the activity of key enzymes like cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS), as well as downregulating pro-inflammatory cytokines such as TNF-α and IL-6. Studies, including those published in "Current Opinion in Clinical Nutrition and Metabolic Care," highlight its potential in neuroprotection, cardiovascular health, and even metabolic regulation. Its ability to interact with multiple signaling pathways underscores its broad therapeutic potential as a pleiotropic agent in promoting overall wellness.

Luteolin's robust scientific profile makes it an excellent candidate for inclusion in a wide array of supplement formulations, targeting areas such as cognitive support, immune modulation, and healthy aging. It is often incorporated into complexes designed for brain health due to its ability to cross the blood-brain barrier and exert neuroprotective effects, as evidenced by studies in the "Journal of Neuroinflammation." For optimal efficacy and safety, sourcing high-purity luteolin, typically standardized to a specific percentage, is critical. Quality considerations include rigorous testing for heavy metals, pesticides, and microbial contaminants to ensure a clean and safe ingredient. Research continues to explore its synergistic effects when combined with other flavonoids or natural compounds, potentially enhancing bioavailability and therapeutic outcomes. Traditional Chinese Medicine has long utilized Sophora japonica for its medicinal properties, lending historical credence to the contemporary scientific investigation of luteolin.