OLIVE LEAF EXTRACT (2O% OLEUROPEIN)

Olive Leaf Extract (OLE), derived from the leaves of the *Olea europaea* L. tree, is a revered botanical with a rich history of traditional use in Mediterranean and Middle Eastern cultures for its health-promoting properties. Our OLE is meticulously standardized to contain 20% Oleuropein, the primary secoiridoid glycoside responsible for many of its observed biological activities. This standardization ensures consistent potency and efficacy, critical for reliable supplement formulation. The extraction process carefully preserves the delicate balance of bioactive compounds found naturally in the olive leaf, ensuring a high-quality ingredient. Historically, olive leaves were used in remedies for fevers and various ailments, highlighting a long-standing recognition of their therapeutic potential. Modern science has begun to validate these traditional uses, focusing on the unique phytochemical profile that distinguishes this powerful botanical from other plant extracts. This commitment to standardization and purity makes it an ideal choice for advanced supplement formulations targeting specific health outcomes. Its distinct characteristics and robust profile make it a sought-after ingredient in the nutraceutical industry.

The profound health benefits of Olive Leaf Extract are largely attributed to its complex array of polyphenolic compounds, with oleuropein being the most prominent, alongside hydroxytyrosol, tyrosol, and verbascoside. Scientific research suggests that these compounds exert powerful antioxidant effects by scavenging free radicals and upregulating endogenous antioxidant enzymes, thereby protecting cellular integrity. Furthermore, OLE demonstrates significant anti-inflammatory properties, potentially through the modulation of inflammatory pathways such as the inhibition of cyclooxygenase (COX) and lipoxygenase (LOX) enzymes, as shown in various in vitro and in vivo studies. Evidence also points to its cardiovascular benefits, including support for healthy blood pressure already within the normal range and maintenance of healthy cholesterol levels. A meta-analysis published in the *Journal of Clinical Hypertension* indicated that OLE supplementation could contribute to reductions in systolic and diastolic blood pressure. Additionally, OLE has been traditionally used and is being researched for its immune-modulating effects, supporting the body's natural defenses against various challenges.

In supplement formulation, Olive Leaf Extract (20% Oleuropein) is highly versatile, finding application in capsules, tablets, and powdered blends designed for immune support, cardiovascular health, and general wellness. The consistent standardization to 20% oleuropein is crucial for formulators to ensure predictable dosing and efficacy, aligning with regulatory guidelines and consumer expectations for quality. Rigorous quality control measures, including testing for heavy metals, pesticides, and microbial contaminants, are essential to guarantee the purity and safety of the raw material. Clinical research continues to expand our understanding of OLE's mechanisms; for instance, a study published in *Phytotherapy Research* demonstrated the ability of oleuropein to improve endothelial function. The synergistic action of oleuropein with other olive leaf polyphenols enhances its overall biological activity, providing a comprehensive ingredient for promoting systemic health. This evidence-based approach to formulation allows for the creation of targeted products that leverage the full spectrum of benefits offered by this ancient botanical.