Red Wine Extract (Vitis vinifera)(fruit)(std. to 20% polyphenols)

Red Wine Extract, derived from the fruit of Vitis vinifera grapes, is a potent botanical ingredient renowned for its rich concentration of bioactive compounds. This specific extract is standardized to contain 20% polyphenols, a diverse group of plant metabolites known for their significant health-promoting properties. The meticulous extraction process ensures the preservation of these delicate compounds, capturing the essence of red wine's beneficial constituents without the alcohol. Historically, the consumption of red wine has been associated with the "French Paradox," a phenomenon where populations with diets high in saturated fats exhibit lower incidences of cardiovascular disease, often attributed to the moderate intake of red wine and its phenolic content. This extract provides a concentrated, consistent, and convenient form of these beneficial phytochemicals, offering a standardized approach to harnessing the grape's natural protective elements for various health applications in the supplement industry.

The health benefits of Red Wine Extract are primarily attributed to its robust polyphenol profile, which includes well-researched compounds such as resveratrol, anthocyanins, proanthocyanidins, and catechins. These polyphenols exert their effects through multiple mechanisms, notably potent antioxidant activity. They scavenge free radicals, reducing oxidative stress, a key contributor to cellular damage and chronic diseases. Research, including studies published in journals like Circulation and The American Journal of Clinical Nutrition, indicates that these compounds can support cardiovascular health by improving endothelial function, reducing LDL oxidation, and promoting healthy blood pressure levels. Furthermore, the anti-inflammatory properties of grape polyphenols have been demonstrated in preclinical and clinical settings, suggesting their role in modulating inflammatory pathways. Resveratrol, a stilbene compound found in grape skins, has garnered particular attention for its potential to activate sirtuins, enzymes linked to cellular longevity and metabolic regulation.

Red Wine Extract standardized to 20% polyphenols is a versatile ingredient widely utilized in dietary supplements targeting cardiovascular support, anti-aging, and general wellness formulations. Its consistent standardization ensures reliable dosing and efficacy, which is crucial for product development and consumer trust. Quality considerations include sourcing grapes from reputable regions, ensuring solvent-free extraction methods, and rigorous testing for purity and contaminant absence. Scientific evidence supporting its use is extensive; for instance, a meta-analysis in Nutrients highlighted the positive impact of grape-derived polyphenols on blood pressure and lipid profiles. Clinical trials have also explored its effects on cognitive function and skin health, further broadening its application potential. Formulators often combine Red Wine Extract with other antioxidants like Vitamin C or E, or ingredients that support circulation such as L-arginine, to create synergistic effects. Its powder form allows for easy incorporation into capsules, tablets, and functional food matrices, making it a highly desirable ingredient for advanced supplement formulations.