TRIBUTYRIN 55% (AS COREBIOMEÂ)

Tributyrin 55% (as CoreBiome®) represents a significant advancement in targeted gut health support, delivering a stable and highly bioavailable form of butyric acid. Butyric acid, a crucial short-chain fatty acid (SCFA), is naturally produced by beneficial gut bacteria through the fermentation of dietary fiber. However, direct supplementation with butyrate salts often faces challenges due to rapid absorption in the upper gastrointestinal tract and an unpleasant odor. CoreBiome®'s tributyrin is a triglyceride composed of three butyrate molecules, offering a more stable and efficient delivery system. This innovative structure allows for a sustained release of butyrate directly to the colon, where it exerts its most profound benefits. CoreBiome® is specifically engineered to overcome the limitations of conventional butyrate sources, ensuring maximum impact on intestinal health.

The health benefits of butyrate are extensive, primarily revolving around its critical role in maintaining gut homeostasis. As the primary energy source for colonocytes (cells lining the colon), butyrate supports their vitality and function, which is essential for a robust intestinal barrier. Scientific research indicates that butyrate strengthens tight junctions between colonocytes, reducing intestinal permeability and mitigating "leaky gut" syndrome. Furthermore, butyrate acts as a potent anti-inflammatory agent in the gut, primarily through its ability to inhibit histone deacetylase (HDAC) enzymes. This epigenetic mechanism modulates gene expression, leading to a reduction in pro-inflammatory cytokine production and a promotion of immune balance within the gut-associated lymphoid tissue (GALT). Studies have also shown butyrate's capacity to positively influence the gut microbiota composition, fostering a diverse and healthy microbial ecosystem.

Tributyrin 55% (CoreBiome®) is an ideal ingredient for a wide range of supplement formulations aimed at enhancing digestive and overall health. Its neutral odor and taste, coupled with its excellent stability, make it highly suitable for various product applications, including powders, capsules, and functional foods. Clinical research comparing tributyrin to traditional butyrate forms has demonstrated its superior delivery to the colon, resulting in more sustained and targeted effects. For instance, studies have highlighted CoreBiome®'s ability to reach the distal gut effectively, where it can support mucosal integrity and exert its anti-inflammatory actions directly. Formulators often combine tributyrin with prebiotics (like FOS or GOS) to further nourish butyrate-producing bacteria or with probiotics to create comprehensive gut health solutions. Ensuring the purity and concentration of tributyrin, such as in the 55% standardized CoreBiome® variant, is paramount for achieving consistent and reliable efficacy in finished products, aligning with stringent quality standards.