Nitric Oxide Booster

Nitric oxide (NO) serves as a critical signaling molecule in cardiovascular physiology, regulating vascular tone, blood flow, and oxygen delivery to tissues. Our NO2 formula combines L-Citrulline DL-Malate (400mg) and L-Arginine compounds (400mg total) to support both immediate and sustained NO production. L-Citrulline bypasses intestinal arginase, resulting in greater plasma arginine elevation than arginine supplementation alone - a phenomenon known as the 'citrulline paradox.'

The dual-pathway approach utilizing both L-Arginine HCl and L-Arginine Alpha-Ketoglutarate ensures optimal NO synthesis through the classical L-arginine-NO synthase pathway. Clinical studies demonstrate that citrulline-malate supplementation can increase exercise performance by 20%, reduce muscle soreness by 40%, and improve ATP production by 34% during exercise. The malate component enhances aerobic energy production through Krebs cycle optimization.

Cardiovascular benefits extend beyond exercise, with studies showing 5-10 mmHg reductions in blood pressure and improved endothelial function markers. The vasodilation effects enhance nutrient and oxygen delivery to all tissues, supporting recovery, cognitive function, and overall vitality. Regular supplementation has been associated with improved arterial compliance and reduced arterial stiffness, markers of cardiovascular aging. The synergistic formula supports both athletic performance and long-term cardiovascular health.