MANGANESE (AS MANGANESE AMINO ACID CHELATE) (20%)

Manganese is an indispensable trace mineral, vital for numerous physiological processes within the human body. This MANGANESE AMINO ACID CHELATE (20%) offers a superior, highly bioavailable form of this essential nutrient. The chelation process involves binding manganese to amino acids, typically glycine, which significantly enhances its absorption and utilization compared to inorganic mineral salts. This advanced delivery system ensures that the mineral is protected during digestion, allowing for efficient uptake into the bloodstream and target tissues. While manganese is naturally found in various foods such as whole grains, nuts, legumes, and leafy green vegetables, dietary intake can often be inconsistent or insufficient to meet optimal requirements, making a well-formulated supplement crucial. This 20% concentration ensures a potent and standardized ingredient for precise formulation applications, emphasizing purity and efficacy.

Manganese functions primarily as a critical cofactor for a diverse array of enzymes, playing a pivotal role in antioxidant defense, bone development, and metabolic regulation. Most notably, it is an integral component of superoxide dismutase (MnSOD), a powerful antioxidant enzyme localized in the mitochondria, which is essential for neutralizing reactive oxygen species and mitigating oxidative stress. Research, such as studies published in the Journal of Biological Chemistry, underscores MnSOD's protective role against cellular damage. Furthermore, manganese is crucial for the synthesis of proteoglycans and collagen, fundamental components of connective tissues, cartilage, and bone matrix. Its involvement in bone mineralization is well-documented, with studies indicating its importance for maintaining bone density and integrity, particularly in conjunction with other bone-supporting minerals.

In supplement formulations, Manganese Amino Acid Chelate (20%) is highly valued for its enhanced bioavailability and stability. It is frequently incorporated into multivitamin/mineral complexes, specialized bone and joint health formulas, and antioxidant blends due to its multifaceted benefits. Quality considerations for this ingredient include stringent heavy metal testing, ensuring purity, and verifying the integrity of the amino acid chelate structure to guarantee optimal absorption and minimize gastrointestinal discomfort. Scientific evidence consistently supports the superior absorption of amino acid chelates over inorganic forms, a principle validated by decades of nutritional research, including work by the late Dr. H. DeWayne Ashmead. This ensures that formulators can deliver an effective and well-tolerated manganese source, optimizing health outcomes by supporting crucial enzymatic functions, robust bone health, and comprehensive antioxidant protection.