CRANBERRY EXTRACT 10:1 (VACCINIUM MACROCARPON)(BERRY)

Cranberry Extract 10:1, derived from the fruit of Vaccinium macrocarpon, is a highly concentrated botanical ingredient prized for its rich phytochemical profile. This extract is typically standardized to a 10:1 ratio, meaning ten parts of raw cranberry material are concentrated into one part of the finished extract, enhancing its potency. Native to North America, cranberries have been traditionally utilized for centuries by indigenous populations for their health-promoting properties, particularly in supporting urinary tract health. The berries themselves are characterized by their tart taste and vibrant red hue, indicative of their high concentration of polyphenolic compounds. Modern processing techniques ensure that the beneficial constituents of the cranberry are preserved and concentrated, providing a potent ingredient for dietary supplements. This concentrated form offers a convenient and effective way to harness the natural advantages of cranberries, making it a staple in various health formulations globally.

The primary health benefits of Cranberry Extract 10:1 are largely attributed to its unique composition of A-type proanthocyanidins (PACs). These specific PACs are recognized for their anti-adhesion properties, particularly against uropathogenic E. coli (UPEC) in the urinary tract. Research suggests that PACs prevent bacteria from adhering to the epithelial cells lining the bladder, thereby supporting urinary tract health and reducing the likelihood of infection. Beyond PACs, cranberry also contains other potent antioxidants, including flavonoids like quercetin and myricetin, and phenolic acids such as ellagic acid. These compounds contribute to the extract's overall antioxidant capacity, helping to combat oxidative stress throughout the body. Studies, such as those published in the American Journal of Clinical Nutrition, have investigated the dose-dependent effects of PACs on bacterial anti-adhesion activity, solidifying the scientific basis for cranberry's efficacy. The synergistic action of these bioactive components provides comprehensive support beyond just the urinary system, extending to general immune and cardiovascular health.

Cranberry Extract 10:1 is a versatile ingredient widely incorporated into various supplement formulations, including capsules, tablets, and powdered drink mixes. Its concentrated nature makes it suitable for achieving effective dosages in smaller serving sizes. When selecting a cranberry extract, quality considerations are paramount; standardization to a specific PAC content, often quantified using validated methods like the DMAC assay, ensures consistent potency and efficacy. Clinical trials have consistently demonstrated that regular consumption of cranberry products, especially those standardized for PACs, can significantly reduce the recurrence of urinary tract infections in susceptible populations. For instance, a meta-analysis published in the Cochrane Database of Systematic Reviews supports the role of cranberry products in preventing UTIs in women. Furthermore, emerging research explores its potential benefits for cardiovascular health by influencing lipid profiles and endothelial function, as well as its prebiotic effects which could support gut microbiome balance. Formulators often combine cranberry extract with other synergistic ingredients like D-mannose or probiotics to enhance its overall effectiveness, creating comprehensive wellness solutions.